Experiment with rapamycin leads to unexpected side effects

Bryan Johnson, a tech entrepreneur renowned for his ambitious anti-aging endeavors, has ceased using the drug rapamycin after nearly five years of experimentation. Johnson, who invests approximately $2 million annually in efforts to reverse his biological age, revealed that the drug may have inadvertently accelerated aging rather than mitigating it.

In a recent YouTube video, Johnson detailed his experiences with rapamycin, an immunosuppressant often discussed in longevity research circles. He reported several adverse effects, including mouth ulcers, delayed wound healing, cholesterol imbalances, elevated blood sugar levels, and an increased resting heart rate. These complications prompted him to discontinue the medication.

Commitment to transparency in the biohacking journey

Addressing his audience, Johnson emphasized the importance of sharing both successes and failures in the pursuit of longevity. “To those of you laughing at home, I’m laughing with you,” he remarked, underscoring his dedication to openness. He further stated, “It’s important to talk about both the successes and the failures. That’s how we all learn.”

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Known for his extreme anti-aging protocols, Johnson has previously engaged in unconventional practices, including a “multigenerational plasma exchange” with his 17-year-old son, Talmage. This involved transfusing his son’s blood into his own system as part of his quest to rejuvenate his body.

Launch of ‘Don’t Die’ movement aims to ‘solve death’

In addition to his personal biohacking experiments, Johnson has initiated a movement he describes as a new “religion” aimed at “solving death” and “saving” the human race. Dubbed “Don’t Die,” the movement seeks to integrate artificial intelligence and advanced technologies to extend human lifespan and enhance quality of life. Johnson envisions this ideology as a “universal translator and the grand unifying theory of existence,” addressing what he perceives as limitations in current frameworks governing civic matters, wealth, and spirituality.

As Johnson continues to navigate the complexities of longevity science, his experiences underscore the experimental nature of biohacking and the necessity for rigorous evaluation of emerging therapies.

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